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Total Synthesis of (−)-Ambiguine P

J. Am. Chem. Soc., 2019, 141(12), pp 4820–4823
DOI:10.1021/jacs.9b01739 full text link

文献汇报人:郑少龙

汇报日期: 2019420

图文摘要:


  • 推荐原因:
  • 一个完美的全合成需要依靠一些高效的方法学来构建关键环系,本篇文章通过[4+3]环加成反映,高效的构建了关键骨架的7元环,使得合成变得高效简洁,也给此类天然产物的合成提供了思路和战略。

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