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Home » total synthesis » Twelve-Step Asymmetric Synthesis of (−)-Nodulisporic Acid C

Twelve-Step Asymmetric Synthesis of (−)-Nodulisporic Acid C

10J. Am. Chem. Soc.2018140 (40), pp 12770–12774. DOI: 10.1021/jacs.8b09965
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文献汇报人:赵志文

汇报日期: 20181013

图文摘要:


  • 推荐原因:

吲哚组装和两个多环化的汇聚式策略极大的缩短了(−)-Nodulisporic Acid C的合成路线,自由基串联环化以及金催化的高效构建立体专一的三环骨架充分展现了该合成策略的高效性。


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